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Sistonen Lab

Feel the heat, experience the shock

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Since its inception in 1994, the Sistonen Lab aims at revealing the fundamental mechanisms that regulate gene expression and chromatin structure in response to intracellular and environmental signals. We have demonstrated that heat shock transcription factors (HSFs) act as integrators in cell stress, reproduction, and cancer.

Research

The research being made in our lab:

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Group Members

Principal Investigator Senior Researchers and Postdoctoral Fellows PhD Students Previous Lab Members Anna AaltoJohanna AhlskogTero-Pekka AlastaloJulius AnckarSusanna AiraksinenJudith BeerHeidi BergmanJohanna BjörkMalin BlomHenri BlomsterMarek BudzyńskiIdalis CardonaZhanna ChitikovaAlexandra ElsingCaroline Haldin-BreitensteinVille HietakangasSamu HimanenCarina HolmbergMaria JensenJenny Joutsen Lila Kallio (neé Pirkkala)Sara KangaspeskaEmine LundstenHeidi LustigTerhi Maula (neé Kuru)Annika MeinanderSatu OrasniemiBeata PaziewskaMarkus PenttinenSandra PihlströmJulia RantaHelena SaarentoAnton SandqvistCynthia SwanPetra VainioJenni VasaraAnniina VihervaaraMalin…

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New publication out in Nucleic Acids Research!

STRESS-SPECIFIC GENOME-WIDE PROGRAMS OF GENES AND ENHANCERS Cells are exposed to various types of cytotoxic stress including oxidative stress, elevated temperatures and toxins. Surviving stressful conditions requires extensive reprogramming of transcription, which involves both upregulation and downregulation of genes. Heat shock has provided an excellent model to investigate how nascent transcription is regulated in cells…

Read more New publication out in Nucleic Acids Research!

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Tykistökatu 6A

The Sistonen Lab

Faculty of Science and Engineering
Åbo Akademi University
Turku Centre for Biotechnology
Biocity, 2nd Floor
Tykistökatu 6A
20520 Turku, Finland

Principal investigator

Prof. Lea Sistonen
Phone: +358-2-215-3311
Fax: +358-2-251-7013
Email: lea.sistonen[at]abo.fi or lea.sistonen[at]bioscience.fi

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