Since its inception in 1994, the Sistonen Lab aims at revealing the fundamental mechanisms that regulate gene expression and chromatin structure in response to intracellular and environmental signals. We have demonstrated that heat shock transcription factors (HSFs) act as integrators in cell stress, reproduction, and cancer.

Research
The research being made in our lab:

Group Members
Principal Investigator × Principal Investigator Lea Sistonen Professor of Molecular Cell Biology Publications lea.sistonen[at]btk.fi, lea.sistonen[at]abo.fi Photo by Nicklas Hägen Senior Researchers and Postdoctoral Fellows × Eva Henriksson eva.henriksson[at]abo.fi I am investigating how HSFs regulate a developmental process, i.e. spermatogenesis, and how they sustain malignant growth in cancer and promote cancer cell invasion. My special focus…

Funding from Jane and Aatos Erkko Foundation to Lea Sistonen and John Eriksson
The research groups of Lea Sistonen & John E. Eriksson receive 968.000 € for a research project to specifically target HPV-Driven.
Read more Funding from Jane and Aatos Erkko Foundation to Lea Sistonen and John Eriksson