1. HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation.
    Kijima T, Prince TL, Tigue ML, Yim KH, Schwartz H, Beebe K, Lee S, Budzynski MA, Williams H, Trepel JB, Sistonen L, Calderwood S, Neckers L.
    Sci Rep. 2018 May 3;8(1):6976
  2. Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer.
    Murillo-Garzón V, Gorroño-Etxebarria I, Åkerfelt M, Puustinen MC, Sistonen L, Nees M, Carton J, Waxman J, Kypta RM.
    Nat Commun. 2018 May 1;9(1):1747.
  3. The VIII International Congress on Stress Proteins in Biology and Medicine: täynnä henkeä.
    Bonorino C, Sistonen L, Eriksson J, Mezger V, Santoro G, Hightower LE.
    Cell Stress Chaperones. 2018 Mar;23(2):171-177
  4. Sumoylation of Notch1 represses its target gene expression during cell stress.
    Antila CJM, Rraklli V, Blomster HA, Dahlström KM, Salminen TA, Holmberg J, Sistonen L, Sahlgren C.
    Cell Death Differ. 2018 Mar;25(3):600-615.
  5. Transcriptional response to stress is pre-wired by promoter and enhancer architecture.
    Vihervaara A, Mahat DB, Guertin MJ, Chu T, Danko CG, Lis JT, Sistonen L.
    Nat Commun. 2017 Aug 15;8(1):255.
  6. Chaperone co-inducer BGP-15 inhibits histone deacetylases and enhances the heat shock response through increased chromatin accessibility.
    Budzyński MA, Crul T, Himanen SV, Toth N, Otvos F, Sistonen L, Vigh L.
    Cell Stress and Chaperones. 2017 Sep;22(5):717-728.
  7. Versatile Functions of Heat Shock Factors: It is Not All About Stress.
    Budzyński MA, Sistonen L.
    Current Immunology Reviews. 2017 Apr;13(1):4-18.
  8. PDF.

  9. Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.
    Karvinen S, Silvennoinen M, Vainio P, Sistonen L, Koch LG, Britton SL, Kainulainen H.
    Exp Gerontol. 2016 Jun 15;79:46-54.
  10. Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors.
    Jaeger AM, Pemble CW 4th, Sistonen L, Thiele DJ.
    Nat Struct Mol Biol. 2016 Feb;23(2):147-54.
  11. Global SUMOylation on active chromatin is an acute heat stress response restricting transcription.
    Niskanen EA, Malinen M, Sutinen P, Toropainen S, Paakinaho V, Vihervaara A, Joutsen J, Kaikkonen MU, Sistonen L, Palvimo JJ.
    Genome Biol. 2015 Jul 28;16:153.
  12. Heat-shock factor 2 is a suppressor of prostate cancer invasion.
    Björk JK, Åkerfelt M, Joutsen J, Puustinen MC, Cheng F, Sistonen L, Nees M.
    Oncogene. 2016 Apr 7;35(14):1770-84.
  13. Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation.
    Budzyński MA, Puustinen MC, Joutsen J, Sistonen L.
    Mol Cell Biol. 2015 Jul;35(14):2530-40.
  14. Cellular stress response cross talk maintains protein and energy homeostasis.
    Swan CL, Sistonen L.
    EMBO J. 2015 Feb 3;34(3):267-9.
  15. Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival.
    Elsing AN, Aspelin C, Björk JK, Bergman HA, Himanen SV, Kallio MJ, Roos-Mattjus P, Sistonen L.
    J Cell Biol. 2014 Sep 15;206(6):735-49.

  16. Heat shock in the springtime.
    Morano KA, Sistonen L, Mezger V.
    Cell Stress Chaperones. 2014 Nov;19(6):753-61.
  17. HSF1 at a glance.
    Vihervaara A, Sistonen L.
    J Cell Sci. 2014 Jan 15;127(Pt 2):261-6.
  18. Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells.
    Vihervaara A, Sergelius C, Vasara J, Blom MA, Elsing AN, Roos-Mattjus P, Sistonen L.
    Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3388-97.
  19. Protein inhibitor of activated STAT3 (PIAS3) protein promotes SUMOylation and nuclear sequestration of the intracellular domain of ErbB4 protein.
    Sundvall M, Korhonen A, Vaparanta K, Anckar J, Halkilahti K, Salah Z, Aqeilan RI, Palvimo JJ, Sistonen L, Elenius K.
    J Biol Chem. 2012 Jun 29;287(27):23216-26.
  20. Regulation of HSF1 function in the heat stress response: implications in aging and disease.
    Anckar J, Sistonen L.
    Annu Rev Biochem. 2011;80:1089-115.
  21. Regulation of the members of the mammalian heat shock factor family.
    Björk JK, Sistonen L.
    FEBS J. 2010 Oct;277(20):4126-39.
  22. Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stress.
    Ahlskog JK, Björk JK, Elsing AN, Aspelin C, Kallio M, Roos-Mattjus P, Sistonen L.
    Mol Cell Biol. 2010 Dec;30(24):5608-20.
  23. Heat shock transcription factor 1 localizes to sex chromatin during meiotic repression.
    Åkerfelt M, Vihervaara A, Laiho A, Conter A, Christians ES, Sistonen L, Henriksson E.
    J Biol Chem. 2010 Nov 5;285(45):34469-76.
  24. miR-18, a member of Oncomir-1, targets heat shock transcription factor 2 in spermatogenesis.
    Björk JK, Sandqvist A, Elsing AN, Kotaja N, Sistonen L.
    Development. 2010 Oct;137(19):3177-84.
  25. Heat shock factors: integrators of cell stress, development and lifespan.
    Åkerfelt M, Morimoto RI, Sistonen L.
    Nat Rev Mol Cell Biol. 2010 Aug;11(8):545-55.
  26. In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification.
    Blomster HA, Imanishi SY, Siimes J, Kastu J, Morrice NA, Eriksson JE, Sistonen L.
    J Biol Chem. 2010 Jun 18;285(25):19324-9.
  27. TransLISA, a novel quantitative, nonradioactive assay for transcription factor DNA-binding analyses.
    Vuori KA, Ahlskog JK, Sistonen L, Nikinmaa M.
    FEBS J. 2009 Dec;276(24):7366-74.
  28. Novel proteomics strategy brings insight into the prevalence of SUMO-2 target sites.
    Blomster HA, Hietakangas V, Wu J, Kouvonen P, Hautaniemi S, Sistonen L.
    Mol Cell Proteomics. 2009 Jun;8(6):1382-90.
  29. Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1.
    Westerheide SD, Anckar J, Stevens SM Jr, Sistonen L, Morimoto RI.
    Science. 2009 Feb 20;323(5917):1063-6.
  30. Mammalian heat shock factor 1 is essential for oocyte meiosis and directly regulates Hsp90alpha expression.
    Metchat A, Åkerfelt M, Bierkamp C, Delsinne V, Sistonen L, Alexandre H, Christians ES.
    J Biol Chem. 2009 Apr 3;284(14):9521-8.
  31. Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli.
    Sandqvist A, Björk JK, Akerfelt M, Chitikova Z, Grichine A, Vourc’h C, Jolly C, Salminen TA, Nymalm Y, Sistonen L.
    Mol Biol Cell. 2009 Mar;20(5):1340-7.
  32. Promoter ChIP-chip analysis in mouse testis reveals Y chromosome
    occupancy by HSF2.

    Åkerfelt M, Henriksson E, Laiho A, Vihervaara A, Rautoma K, Kotaja N, Sistonen L.
    Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11224-9.
  33. SUMO: getting it on.
    Anckar J, Sistonen L.
    Biochem Soc Trans. 2007 Dec;35(Pt 6):1409-13.
  34. Evidence that the p38 MAP kinase pathway is dysregulated in HLA-B27-expressing human monocytic cells: correlation with HLA-B27 misfolding.
    Sahlberg AS, Penttinen MA, Heiskanen KM, Colbert RA, Sistonen L, Granfors K.
    Arthritis Rheum. 2007 Aug;56(8):2652-62.
  35. Heat shock factors at a crossroad between stress and development.
    Åkerfelt M, Trouillet D, Mezger V, Sistonen L.
    Ann N Y Acad Sci. 2007 Oct;1113:15-27.
  36. Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell line.
    Nagy E, Balogi Z, Gombos I, Akerfelt M, Björkbom A, Balogh G, Török Z, Maslyanko A, Fiszer-Kierzkowska A, Lisowska K, Slotte PJ, Sistonen L, Horváth I, Vígh L.
    Proc Natl Acad Sci U S A. 2007 May 8;104(19):7945-50.
  37. Fever-like hyperthermia controls T Lymphocyte persistence by inducing degradation of cellular FLIPshort.
    Meinander A, Söderström TS, Kaunisto A, Poukkula M, Sistonen L, Eriksson JE.
    J Immunol. 2007 Mar 15;178(6):3944-53.
  38. Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1.
    Östling P, Björk JK, Roos-Mattjus P, Mezger V, Sistonen L.
    J Biol Chem. 2007 Mar 9;282(10):7077-86.
  39. Heat shock factor 1 as a coordinator of stress and developmental pathways.
    Anckar J, Sistonen L.
    Adv Exp Med Biol. 2007;594:78-88.
  40. Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression.
    Chang Y, Östling P, Åkerfelt M, Trouillet D, Rallu M, Gitton Y, El Fatimy R, Fardeau V, Le Crom S, Morange M, Sistonen L, Mezger V.
    Genes Dev. 2006 Apr 1;20(7):836-47.
  41. Clustering of heat-shock factors.
    Björk JK, Sistonen L.
    Biochem J. 2006 Apr 1;395(1):e5-6.
  42. Inhibition of DNA binding by differential sumoylation of heat shock factors.
    Anckar J, Hietakangas V, Denessiouk K, Thiele DJ, Johnson MS, Sistonen L.
    Mol Cell Biol. 2006 Feb;26(3):955-64.
  43. PDSM, a motif for phosphorylation-dependent SUMO modification.
    Hietakangas V, Anckar J, Blomster HA, Fujimoto M, Palvimo JJ, Nakai A, Sistonen L.
    Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):45-50.
  44. Rapid turnover of c-FLIPshort is determined by its unique C-terminal tail.
    Poukkula M, Kaunisto A, Hietakangas V, Denessiouk K, Katajamäki T, Johnson MS, Sistonen L, Eriksson JE.
    J Biol Chem. 2005 Jul 22;280(29):27345-55.
  45. CD95-mediated alteration in Hsp70 levels is dependent on protein stabilization.
    Concannon CG, FitzGerald U, Holmberg CI, Szegezdi E, Sistonen L, Samali A.
    Cell Stress Chaperones. 2005 Spring;10(1):59-65.
  46. Enhanced intracellular replication of Salmonella enteritidis in HLA-B27-expressing human monocytic cells: dependency on glutamic acid at position 45 in the B pocket of HLA-B27.
    Penttinen MA, Heiskanen KM, Mohapatra R, DeLay ML, Colbert RA, Sistonen L, Granfors K.
    Arthritis Rheum. 2004 Jul;50(7):2255-63.
  47. The ubiquitin-proteasome pathway.
    Roos-Mattjus P, Sistonen L.
    Ann Med. 2004;36(4):285-95.
  48. Nuclear stress granules: the awakening of a sleeping beauty?
    Sandqvist A, Sistonen L.
    J Cell Biol. 2004 Jan 5;164(1):15-7.
  49. Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.
    Tran SE, Meinander A, Holmström TH, Rivero-Müller A, Heiskanen KM, Linnau EK, Courtney MJ, Mosser DD, Sistonen L, Eriksson JE.
    Cell Death Differ. 2003 Oct;10(10):1137-47.
  50. Formation of nuclear stress granules involves HSF2 and coincides with the nucleolar localization of Hsp70.
    Alastalo TP, Hellesuo M, Sandqvist A, Hietakangas V, Kallio M, Sistonen L.
    J Cell Sci. 2003 Sep 1;116(Pt 17):3557-70.
  51. Stressor-dependent regulation of the heat shock response in zebrafish, Danio rerio.
    Airaksinen S, Råbergh CM, Lahti A, Kaatrasalo A, Sistonen L, Nikinmaa M.
    Comp Biochem Physiol A Mol Integr Physiol. 2003 Apr;134(4):839-46.
  52. Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1.
    Hietakangas V, Ahlskog JK, Jakobsson AM, Hellesuo M, Sahlberg NM, Holmberg CI, Mikhailov A, Palvimo JJ, Pirkkala L, Sistonen L.
    Mol Cell Biol. 2003 Apr;23(8):2953-68.
  53. Erythroid differentiation sensitizes K562 leukemia cells to TRAIL-induced apoptosis by downregulation of c-FLIP.
    Hietakangas V, Poukkula M, Heiskanen KM, Karvinen JT, Sistonen L, Eriksson JE.
    Mol Cell Biol. 2003 Feb;23(4):1278-91.
  54. Multisite phosphorylation provides sophisticated regulation of transcription factors.
    Holmberg CI, Tran SE, Eriksson JE, Sistonen L.
    Trends Biochem Sci. 2002 Dec;27(12):619-27.
  55. Reperfusion but not acute ischemia in pig small intestine induces transcriptionally mediated heat shock response in situ.
    Oksala NK, Kaarniranta K, Tenhunen JJ, Tiihonen R, Heino A, Sistonen L, Paimela H, Alhava E.
    Eur Surg Res. 2002 Nov-Dec;34(6):397-404.
  56. HLA-B27 modulates nuclear factor kappaB activation in human monocytic cells exposed to lipopolysaccharide.
    Penttinen MA, Holmberg CI, Sistonen L, Granfors K.
    Arthritis Rheum. 2002 Aug;46(8):2172-80.
  57. From research of cellular stress to various clinical break through innovations?
    Kaarniranta K, Oksala N, Lammi MJ, Helminen HJ, Sistonen L.
    Duodecim. 2001;117(22):2266-72.
  58. Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice.
    Kallio M, Chang Y, Manuel M, Alastalo TP, Rallu M, Gitton Y, Pirkkala L, Loones MT, Paslaru L, Larney S, Hiard S, Morange M, Sistonen L, Mezger V.
    EMBO J. 2002 Jun 3;21(11):2591-601.
  59. Neuronal cells show regulatory differences in the hsp70 gene response.
    Kaarniranta K, Oksala N, Karjalainen HM, Suuronen T, Sistonen L, Helminen HJ, Salminen A, Lammi MJ.
    Brain Res Mol Brain Res. 2002 May 30;101(1-2):136-40.
  60. Genomic organization and promoter analysis of the human heat shock factor 2 gene.
    Nykänen P, Alastalo TP, Ahlskog J, Horelli-Kuitunen N, Pirkkala L, Sistonen L.
    Cell Stress Chaperones. 2001 Oct;6(4):377-85.
  61. Activation of the MKK4-JNK pathway during erythroid differentiation of K562 cells is inhibited by the heat shock factor 2-beta isoform.
    Hietakangas V, Elo I, Rosenström H, Coffey ET, Kyriakis JM, Eriksson JE, Sistonen L.
    FEBS Lett. 2001 Sep 7;505(1):168-72.
  62. Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1.
    Holmberg CI, Hietakangas V, Mikhailov A, Rantanen JO, Kallio M, Meinander A, Hellman J, Morrice N, MacKintosh C, Morimoto RI, Eriksson JE, Sistonen L.
    EMBO J. 2001 Jul 16;20(14):3800-10.
  63. Differential induction of Hsp70-encoding genes in human hematopoietic cells.
    Leppä S, Kajanne R, Arminen L, Sistonen L.
    J Biol Chem. 2001 Aug 24;276(34):31713-9.
  64. Roles of the heat shock transcription factors in regulation of the heat shock response and beyond.
    Pirkkala L, Nykänen P, Sistonen L.
    FASEB J. 2001 May;15(7):1118-31.
  65. Characterization of a hypoxia-inducible factor (HIF-1alpha ) from rainbow trout. Accumulation of protein occurs at normal venous oxygen tension.
    Soitamo AJ, Rabergh CM, Gassmann M, Sistonen L, Nikinmaa M.
    J Biol Chem. 2001 Jun 8;276(23):19699-705.
  66. Primary chondrocytes resist hydrostatic pressure-induced stress while primary synovial cells and fibroblasts show modified Hsp70 response.
    Kaarniranta K, Holmberg CI, Lammi MJ, Eriksson JE, Sistonen L, Helminen HJ.
    Osteoarthritis Cartilage. 2001 Jan;9(1):7-13.
  67. Heat shock factor 2 is activated during mouse heart development.
    Eriksson M, Jokinen E, Sistonen L, Leppä S.
    Int J Dev Biol. 2000 Aug;44(5):471-7.
  68. Formation of nuclear HSF1 granules varies depending on stress stimuli.
    Holmberg CI, Illman SA, Kallio M, Mikhailov A, Sistonen L.
    Cell Stress Chaperones. 2000 Jul;5(3):219-28.
  69. Heat-shocked A20 lymphoma cells fail to induce degranulation of cytotoxic T lymphocytes: possible mechanism of resistance.
    Jackson KM, DeLeon M, Sistonen L, Verret CR.
    Cell Immunol. 2000 Jul 10;203(1):12-8.
  70. Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic pressurization and elevated temperature.
    Kaarniranta K, Holmberg CI, Helminen HJ, Eriksson JE, Sistonen L, Lammi MJ.
    FEBS Lett. 2000 Jun 23;475(3):283-6.
  71. Tissue-specific expression of zebrafish (Danio rerio) heat shock factor 1 mRNAs in response to heat stress.
    Råbergh CM, Airaksinen S, Soitamo A, Björklund HV, Johansson T, Nikinmaa M, Sistonen L.
    J Exp Biol. 2000 Jun;203(Pt 12):1817-24.
  72. Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway.
    Pirkkala L, Alastalo TP, Zuo X, Benjamin IJ, Sistonen L.
    Mol Cell Biol. 2000 Apr;20(8):2670-5.
  73. Antibody supershift assay is inadequate for determining HSF stoichiometry in HSE complexes.
    Pirkkala L, Sistonen L.
    Cell Stress Chaperones. 1999 Dec;4(4):259-61.
  74. Thermotolerance and cell death are distinct cellular responses to stress: dependence on heat shock proteins.
    Samali A, Holmberg CI, Sistonen L, Orrenius S.
    FEBS Lett. 1999 Nov 19;461(3):306-10.
  75. Differentiation lineage-specific expression of human heat shock transcription factor 2.
    Pirkkala L, Alastalo TP, Nykanen P, Seppa L, Sistonen L.
    FASEB J. 1999 Jun;13(9):1089-98.
  76. Conventional and novel PKC isoenzymes modify the heat-induced stress response but are not activated by heat shock.
    Holmberg CI, Roos PM, Lord JM, Eriksson JE, Sistonen L.
    J Cell Sci. 1998 Nov;111 ( Pt 22):3357-65.
  77. Effects of heat shock and hypoxia on protein synthesis in rainbow trout (Oncorhynchus mykiss) cells.
    Airaksinen S, Råbergh CM, Sistonen L, Nikinmaa M.
    J Exp Biol. 1998 Sep;201(Pt 17):2543-51.
  78. Stage-specific expression and cellular localization of the heat shock factor 2 isoforms in the rat seminiferous epithelium.
    Alastalo TP, Lönnström M, Leppä S, Kaarniranta K, Pelto-Huikko M, Sistonen L, Parvinen M.
    Exp Cell Res. 1998 Apr 10;240(1):16-27.
  79. Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation.
    Kaarniranta K, Elo M, Sironen R, Lammi MJ, Goldring MB, Eriksson JE, Sistonen L, Helminen HJ.
    Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2319-24.
  80. Suppression of Fas/APO-1-mediated apoptosis by mitogen-activated kinase signaling.
    Holmström TH, Chow SC, Elo I, Coffey ET, Orrenius S, Sistonen L, Eriksson JE.
    J Immunol. 1998 Mar 15;160(6):2626-36.
  81. Thioredoxin is transcriptionally induced upon activation of heat shock factor 2.
    Leppä S, Pirkkala L, Chow SC, Eriksson JE, Sistonen L.
    J Biol Chem. 1997 Nov 28;272(48):30400-4.
  82. Overexpression of HSF2-beta inhibits hemin-induced heat shock gene expression and erythroid differentiation in K562 cells.
    Leppä S, Pirkkala L, Saarento H, Sarge KD, Sistonen L.
    J Biol Chem. 1997 Jun 13;272(24):15293-8.
  83. The phorbol ester 12-O-tetradecanoylphorbol 13-acetate enhances the heat-induced stress response.Holmberg CI, Leppä S, Eriksson JE, Sistonen L.
    J Biol Chem. 1997 Mar 7;272(10):6792-8.
  84. Heat shock response–pathophysiological implications.
    Leppä S, Sistonen L.
    Ann Med. 1997 Feb;29(1):73-8.
  85. Cell transformation by c-Ha-rasVal12 oncogene is accompanied by a decrease in histone H1 zero and an increase in nucleosomal repeat length.
    Laitinen J, Sistonen L, Alitalo K, Hölttä E.
    J Cell Biochem. 1995 Jan;57(1):1-11.
  86. Deficient induction of human hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1.
    Mathur SK, Sistonen L, Brown IR, Murphy SP, Sarge KD, Morimoto RI.
    Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8695-9.
  87. Stress induction of the mammalian GRP78/BiP protein gene: in vivo genomic footprinting and identification of p70CORE from human nuclear extract as a DNA-binding component specific to the stress regulatory element.
    Li WW, Sistonen L, Morimoto RI, Lee AS.
    Mol Cell Biol. 1994 Aug;14(8):5533-46.
  88. Arachidonate is a potent modulator of human heat shock gene transcription.
    Jurivich DA, Sistonen L, Sarge KD, Morimoto RI.
    Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2280-4.
  89. Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription.
    Sistonen L, Sarge KD, Morimoto RI.
    Mol Cell Biol. 1994 Mar;14(3):2087-99.
  90. Ca2+ and Zn2+ dependence of DNA synthesis in untransformed and in Ha-ras(val-12)-expressing NIH 3T3 cells.
    Back CJ, Sistonen L, Enkvist MO, Heikkilä JE, Akerman KE.
    Exp Cell Res. 1993 Sep;208(1):303-10.
  91. Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemia cells.
    Sistonen L, Sarge KD, Phillips B, Abravaya K, Morimoto RI.
    Mol Cell Biol. 1992 Sep;12(9):4104-11.
  92. Antiproliferative prostaglandins activate heat shock transcription factor.
    Amici C, Sistonen L, Santoro MG, Morimoto RI.
    Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6227-31.
  93. Effect of sodium salicylate on the human heat shock response.
    Jurivich DA, Sistonen L, Kroes RA, Morimoto RI.
    Science. 1992 Mar 6;255(5049):1243-5.
  94. Analysis of tyrosine kinase mRNAs including four FGF receptor mRNAs expressed in MCF-7 breast-cancer cells.
    Lehtola L, Partanen J, Sistonen L, Korhonen J, Wärri A, Härkönen P, Clarke R, Alitalo K.
    Int J Cancer. 1992 Feb 20;50(4):598-603.
  95. Nuclear colocalization of cellular and viral myc proteins with HSP70 in myc-overexpressing cells.
    Koskinen PJ, Sistonen L, Evan G, Morimoto R, Alitalo K.
    J Virol. 1991 Feb;65(2):842-51.
  96. Immediate early gene responses of NIH 3T3 fibroblasts and NMuMG epithelial cells to TGF beta-1.
    Koskinen PJ, Sistonen L, Bravo R, Alitalo K.
    Growth Factors. 1991;5(4):283-93.
  97. Constitutively activated neu oncoprotein tyrosine kinase interferes with growth factor-induced signals for gene activation.
    Lehtola L, Sistonen L, Koskinen P, Lehväslaiho H, Di Renzo MF, Comoglio PM, Alitalo K.
    J Cell Biochem. 1991 Jan;45(1):69-81.
  98. c-Ha-rasVal 12 oncogene-transformed NIH-3T3 fibroblasts display more decondensed nucleosomal organization than normal fibroblasts.
    Laitinen J, Sistonen L, Alitalo K, Hölttä E.
    J Cell Biol. 1990 Jul;111(1):9-17.
  99. Downregulation of the early genomic growth factor response in neu oncogene-transformed cells.
    Sistonen L, Koskinen PJ, Lehväslaiho H, Lehtola L, Bravo R, Alitalo K.
    Oncogene. 1990 Jun;5(6):815-21.
  100. Increased erythroid potentiating activity/tissue inhibitor of metalloproteinases and jun/fos transcription factor complex characterize tumor promoter-induced megakaryoblastic differentiation of K562 leukemia cells.
    Alitalo R, Partanen J, Pertovaara L, Hölttä E, Sistonen L, Andersson L, Alitalo K.
    Blood. 1990 May 15;75(10):1974-82.
  101. Regulation by EGF is maintained in an overexpressed chimeric EGFR/neu receptor tyrosine kinase.
    Lehväslaiho H, Sistonen L, diRenzo F, Partanen J, Comoglio P, Hölttä E, Alitalo K.
    J Cell Biochem. 1990 Mar;42(3):123-33.
  102. Activation of the neu tyrosine kinase induces the fos/jun transcription factor complex, the glucose transporter and ornithine decarboxylase.
    Sistonen L, Hölttä E, Lehväslaiho H, Lehtola L, Alitalo K.
    J Cell Biol. 1989 Nov;109(5):1911-9.
  103. Down-regulation of proteolytic activity in 12-O-tetradecanoyl-phorbol-13-acetate-induced K562 leukemia cell cultures: depletion of active urokinase by excess type 1 plasminogen activator inhibitor.
    Alitalo R, Andersson LC, Tapiovaara H, Sistonen L, Vaheri A, Stephens R.
    J Cell Physiol. 1989 Jul;140(1):119-30.
  104. Mechanism of T cell proliferation in vivo: analysis of IL-2 receptor expression and activation of c-myc and c-myb oncogenes during lymphatic regeneration.
    Sihvola M, Sistonen L, Alitalo K, Hurme M.
    Biochem Biophys Res Commun. 1989 Apr 14;160(1):181-8.
  105. Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.
    Pertovaara L, Sistonen L, Bos TJ, Vogt PK, Keski-Oja J, Alitalo K.
    Mol Cell Biol. 1989 Mar;9(3):1255-62.
  106. The cellular response to induction of the p21 c-Ha-ras oncoprotein includes stimulation of jun gene expression.
    Sistonen L, Hölttä E, Mäkelä TP, Keski-Oja J, Alitalo K.
    EMBO J. 1989 Mar;8(3):815-22.
  107. Receptor downregulation and DNA synthesis are modulated by EGF and TPA in cells expressing an EGFR/neu chimera.
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